Henrik Kløverpris’ interest in HIV immunology first piqued at MSc level when, in 2005, he co-ordinated an HIV T-cell vaccine trial in Anders Fomsgaard’s laboratory at the Statens Serum Institute in Copenhagen, Denmark. In 2008 he joined Philip Goulder’s laboratory at the University of Oxford to study the impact of T-cell responses in control of HIV infection at the population level. Naturally, his PhD and Post-doctoral work there led to several visits to South Africa – the epicentre of the global HIV epidemic. When Kløverpris was awarded a research prize from the Danish Research Council in 2012, he used that opportunity to join the Africa Health Research Institute (AHRI) in Durban, South Africa – a place that had left an indelible mark on him. His research was based in the laboratory of Dr Alasdair Leslie – a former colleague from the University of Oxford. At AHRI, Kløverpris has worked to develop a new area of HIV research. He was recently awarded a prestigious Sir Henry Dale Wellcome Trust Fellowship, through University College London, to start his own research group as an AHRI Junior Faculty member. His current work focuses on innate lymphoid cells and mucosal barrier sites in HIV infection using human tissue samples from local hospitals in and around Durban.