This interactive workshop will provide an introduction to basic biostatistical concepts and statistical literacy, introductory reproducible statistical analysis in R, basic data management, and key statistical considerations for the design and analysis of clinical trials. Concepts will be motivated from real-world examples in clinical and laboratory research on HIV vaccines and TB.
After completing this workshop, scholars will be able to:
Understand and explain basic biostatistical concepts;
Apply basic data management principles to create accurate data sets;
Create a reproducible pdf report with basic descriptive and inferential statistics in an R markdown file;
Increase statistical literacy to improve understanding and critical review of the scientific literature;
Describe key clinical trial design features with application to HIV vaccine trials;
Understand fundamental statistical methods relevant to laboratory assay validation/qualification/optimisation.
This 4-day workshop (Tuesday 8h30-3h30, Friday-Sunday 8h30 to 17h30) will involve short lectures with quizzes and interactive group exercises with R examples to apply key concepts. Participants will have the opportunity to meet one-on-one with faculty to answer questions on the material covered and to discuss statistical or data management issues in their own research.
Workshop faculty include:
Zoe Moodie, Senior Staff Scientist, Fred Hutchinson Cancer Research Center, Seattle, USA.
Lori Dodd, Mathematical Statistician, National Institute of Allergy and Infectious Diseases, Maryland, USA.
Martha Nason, Mathematical Statistician, National Institute of Allergy and Infectious Diseases, Maryland, USA.
Michael Duvenhage, Clinical Trials Data Operations Manager, Leidos Biomedical Research Inc., Maryland, USA.
Additional Members of Organising Committee:
Peter Gilbert, Member, Fred Hutchinson Cancer Research Center, Seattle, USA
Thumbi Ndung’u, SANTHE Programme Director
Denis Chopera, SANTHE Programme Executive Manager
Victoria Kasprowicz, SANTHE Senior Strategic Advisor
Who should apply?
Trainees and investigators at the Masters, PhD, or Post-doctoral level with a background in HIV and/or TB research who wish to further their understanding of basic statistical concepts. (Preference will be given to SANTHE and HIV Vaccine Trials Network (HVTN) affilates.)