Many countries, especially countries in Sub-Saharan Africa that are struggling with the HIV epidemic are being encouraged to implement new affordable HIV-related point of care tests. Point of care (POC) diagnostics are simple rapid medical tests that are carried out at or near the patient to generate quick results to allow clinicians to make decisions without delays. Katoba is currently interested in process evaluation of point of care diagnostics. Her study goal is to investigate factors affecting point-of-care implementation and to assess the impact of the implementation on prevention-of-mother to child of HIV transmission. The study will be done in Zambia. A better understanding of implementation factors is of great importance to the decision makers, POC developers, and has potential to impact on PMTCT and overall public health.