Deliberative dialogues in rural South Africa reveal public support and communication challenges in HIV cure research: uMkhanyakude district, KwaZulu-Natal

This study used deliberative group discussions that are informed discussions to investigate the knowledge of HIV cure in rural South Africa. Working with communities as partners has been the main goal of this research. Discovery scientists were given a chance to explain HIV cure science in clear, simple ways, and to have open, meaningful conversations with community members. The discussions allowed participants  to express their views, concerns and questions on participation and engagement.

Participants were generally supportive of finding a cure, saying it would help reduce the harm HIV has caused to people, families, and communities. However, participants also faced challenges in understanding the scientific concepts of cure research. Some were unsure what “cure” means in this context and worried about unrealistic expectations or confusion with current ART treatment. Participants’ questions showed strong interest and a desire to understand the topic. Although this limited deeper discussions, it helped identify knowledge gaps, showed trust in the process, and highlighted the need to share more information in future community discussions on HIV cure research.

Concerns were raised about how research findings would be communicated back to the community, how participation might affect people’s health and well‑being, and whether there would be fair access to the benefits of the research. Participants said that talking clearly, respectfully, and regularly with communities is important for building trust. This helps people understand HIV cure research, the possible risks, and what taking part really means. Their views can guide researchers to plan studies that are responsive to community needs.