Harriet Mayanja-Kizza

SANTHE Consortium Steering Committee Member,
SANTHE Programme Assistant Director

Uganda CWRU Research Collaboration (UCRC) Kampala, Uganda

Collaboration Interests
  • Evidence of COVID-19 asymptomatic infection
  • Interaction with COVID-19 infection
  • TB disease early detection
  • TB in adolescents
  • TB transmission dynamics

Harriet Mayanja-Kizza, a Professor of Medicine at Makerere University in Kampala, Uganda. She is a principal investigator on studies including tuberculosis (TB) immune diagnostics, clinical trials, and immune responses among TB contacts who present with latent TB resistor phenotypes. The immunodiagnostic studies aim at determining a significantly sensitive and specific immune biomarker towards triaging suspected TB patients, as a screening tool in public health settings. Studies also aim at determining surrogate markers for early TB disease, which would also be of benefit in TB vaccine studies towards a surrogate marker of disease, especially in the early pre-clinical stages. Other work includes studies related to the mechanism of resistance to Mycobacterial tuberculosis (Mtb) infection among contacts of close pulmonary TB patients, looking at blood and bronchial lavage samples. These studies would contribute towards better understanding the role of host factors in the risk of active TB disease or ability to control active disease in the face of exposure in high endemic countries.

SANTHE is an Africa Health Research Institute (AHRI) flagship programme funded by the Science for Africa Foundation through the DELTAS Africa programme; the Bill & Melinda Gates Foundation; Gilead Sciences Inc.; and the Ragon Institute of Mass General, MIT, and Harvard.