Jaclyn Mann

SANTHE Researcher/Supervisor Scientific Innovation Awardee

University of KwaZulu-Natal (UKZN) Durban, South Africa


Investigation of the determinants of inter-subtype differences in HIV-1 Gag-drivenreplication capacity and their implications for HIV-1 transmissibility

Collaboration Interests
  • HIV clinical studies
  • Virology

Jaclyn Mann is a senior lecturer and researcher in the HIV Pathogenesis Programme (HPP)
at UKZN where she completed her PhD in Virology. Her research interests include
understanding the effect of immune-driven mutations on HIV replication capacity and inter-
subtype comparisons of HIV protein function to help understand differences in prevalence
and expansion of HIV subtypes. She received a Future Leaders – African Independent
Research (FLAIR) fellowship from the Royal Society and African Academy of Sciences to
characterise HIV variants in reservoirs, which present a barrier to curing HIV.

SANTHE is an Africa Health Research Institute (AHRI) flagship programme funded by the Science for Africa Foundation through the DELTAS Africa programme; the Bill & Melinda Gates Foundation; Gilead Sciences Inc.; and the Ragon Institute of Mass General, MIT, and Harvard.