Simani Gaseitsiwe

Simani Gaseitsiwe works as a Research Associate at BHP. His work focuses on infection biology, aiming to understand how different pathogens interact with the human host. His primary pathogen of interest is HIV and his research on HIV focuses on understanding its diversity and how HIV-1 subtype C responds to antiretroviral therapy (ART) especially the resistance mutations that develop in response to different antiretrovirals. This work has helped optimise HIV treatment and better monitor treatment outcomes in HIV-1C infection. Other pathogens of interest in his research group include hepatitis B virus, Mycobacterium tuberculosis (Mtb), and SARS CoV-2. For these pathogens, Gaseitsiwe’s groups interest has been in understanding the molecular epidemiology of these pathogens in Botswana and how they interact with HIV.