Yiakon Sein

SANTHE Masters Fellow

KEMRI/Wellcome Trust Research Programme (KWTRP) Kilifi, Kenya

African Collaboration for Innovation in HIV/TB Prevention (ACP-HIV/TB) Fellowship Recipient


Determining the diversity of the naive B cell repertoire in African (Kenyan) population

Collaboration Interests
  • Surveillance of HIV within Africa

Yiakon Sein obtained his BSc degree in Medical Laboratory Science at Jomo Kenyatta University of Agriculture and Technology in Juja, Kenya. He has a keen interest in understanding the immunologic response of the human body to infectious diseases and in applying novel technologies for evidence-based decision making towards epidemic control. He is specifically keen on gaining an in-depth understanding of why the HIV virus has been particularly successful in evading host immune responses and using that knowledge to inform the design of prophylactic and therapeutic vaccine strategies.

He currently aims to characterise the overall naïve B cell repertoire in the African population. This will contribute towards providing information on region-specific allelic variants of immunoglobulins, thus improving the relevance of universal databases to the African setting.

SANTHE is an Africa Health Research Institute (AHRI) flagship programme funded by the Science for Africa Foundation through the DELTAS Africa programme; the Bill & Melinda Gates Foundation; Gilead Sciences Inc.; and the Ragon Institute of Mass General, MIT, and Harvard.