Publications

Dysfunctional effector memory CD8 T cells in the bronchoalveolar compartment of people living with HIV

bioRxiv

This article, titled “Dysfunctional effector memory CD8 T cells in the bronchoalveolar compartment of people living with HIV,” explores the immune response in individuals with HIV. The study focuses on a specific type of immune cell called effector memory CD8 T cells, which play a crucial role in fighting infections. The researchers investigate these cells in the bronchoalveolar compartment, which is associated with the respiratory system.

The findings suggest that in people living with HIV, these effector memory CD8 T cells in the bronchoalveolar compartment may not function properly. This dysfunction could potentially contribute to impaired immune responses in the respiratory system. The study provides valuable insights into the immune dynamics of individuals with HIV, particularly in the context of respiratory health. However, it’s important to note that this information is based on a preprint version of the article, and further peer-reviewed research may be needed to validate and expand upon these findings.

Disclaimer: This lay summary was generated by AI and has not been approved by any of the authors yet.

SANTHE is an Africa Health Research Institute (AHRI) flagship programme funded by the Science for Africa Foundation through the DELTAS Africa programme; the Bill & Melinda Gates Foundation; Gilead Sciences Inc.; and the Ragon Institute of Mass General, MIT, and Harvard.