Exposure to common infections may shape basal immunity and potentially HIV-1 acquisition amongst a high-risk population in Coastal Kenya

Front Immunol

The article explores the connection between exposure to common infections and the development of basal immunity, particularly in relation to the risk of acquiring HIV-1 in a high-risk population in Coastal Kenya. Basal immunity refers to the basic level of immune defense that individuals have against infections. The study suggests that experiencing common infections may influence the strength of this basal immunity. The research focuses on a high-risk population in a specific region, shedding light on the potential factors that could affect their susceptibility to HIV-1. Understanding these dynamics may contribute to better strategies for preventing HIV-1 transmission in such populations.

Disclaimer: This lay summary was generated by AI and has not been approved by any of the authors yet.

SANTHE is an Africa Health Research Institute (AHRI) flagship programme funded by the Science for Africa Foundation through the DELTAS Africa programme; the Bill & Melinda Gates Foundation; Gilead Sciences Inc.; and the Ragon Institute of Mass General, MIT, and Harvard.