Perceptions of young people living with HIV and caregivers in Botswana on analytical treatment interruption studies: a qualitative approach

This qualitative study explored how young people living with HIV, their caregivers, healthcare providers and community advocates in Botswana viewed research studies that involve a carefully monitored pause in HIV treatment. The researchers wanted to understand their knowledge of these studies and whether they would be willing to take part in them.

The interviews showed that most participants had little or no previous knowledge of treatment interruption studies. Despite this, many considered this type of research acceptable because they recognised its potential to advance HIV cure research and benefit future generations. Participants also emphasised that such studies should include careful monitoring, clear safety measures and regular communication to protect those taking part.

Young people and caregivers highlighted the importance of receiving clear information about the purpose of the research, the possible risks and benefits, and what would happen during the treatment pause. Trust in the research team and ongoing support throughout the study were also seen as essential.

Overall, the findings suggest that treatment interruption studies are acceptable to many young people living with HIV and their caregivers when appropriate safeguards are in place. The study highlights the importance of community education, transparent communication and participant-centred research when designing future HIV cure studies.

Disclaimer: This lay summary was generated by AI and has not been approved by any of the authors yet.