Fellows

John Kimotho

SANTHE PhD Fellow


KEMRI/Wellcome Trust Research Programme (KWTRP) Kilifi, Kenya

Project

Establishing a population immune baseline in African population: impact of lifelong cumulative exposures on shaping naive B cell repertoire

Collaboration Interests
  • B cell immunology
  • Bio-informatic tools for data analysis
  • Sequencing technologies
Supervisor

John Kimotho is a Kenyan-born biomedical research scientist with a Master’s degree in Immunology from Pwani University in Kilifi, Kenya, funded by the Initiative to Develop African Research Leaders (IDeAL) at the KEMRI–Wellcome Trust Research Programme (KWTRP). He holds an undergraduate degree in Medical Laboratory Science and Technology from the University of Nairobi.

Before beginning his PhD, he worked as an Assistant Research Officer at KWTRP, where he studied immune responses in Kenyan COVID-19 patients with differing disease severity phenotypes.

His PhD research focuses on understanding how lifelong cumulative infectious exposures shape the naïve B cell repertoire in African populations. His work aims to identify predictive immune factors that influence variation in vaccine and pathogen responses, contributing to improved vaccine design considerations tailored to African populations.

SANTHE is an Africa Health Research Institute (AHRI) flagship programme funded by the Science for Africa Foundation through the DELTAS Africa programme; the Gates Foundation; Gilead Sciences Inc.; and the Ragon Institute of Mass General, MIT, and Harvard.