Researchers/Supervisors

Simani Gaseitsiwe

SANTHE Collaborative Grant Awardee,
SANTHE Consortium Steering Committee Member,
SANTHE Scientific Innovation Awardee,
SANTHE Site Principal Investigator


Botswana Harvard Health Partnership (BHP) Gaborone, Botswana

Project

Antibody and T-Cell responses elicited by different SARS-CoV-2 vaccines in Botswana: durability and impact of HIV infection and previous SARS-CoV-2 and prevalent infection

Collaboration Interests
  • Antimicrobial resistance
  • HIV diversity
  • Mycobacterium tuberculosis (Mtb) molecular epidemiology
  • Viral hepatitis

Simani Gaseitsiwe is a Research Associate at the Botswana–Harvard AIDS Institute Partnership (BHP), Gaborone, Botswana. His research focuses on infection biology and the interaction between pathogens and the human host, with a primary emphasis on HIV. He studies HIV-1 subtype C diversity and investigates how the virus responds to antiretroviral therapy, including the emergence of drug resistance mutations. This work contributes to improving HIV treatment optimisation and monitoring of treatment outcomes in subtype C–predominant settings. His broader research interests include hepatitis B virus, Mycobacterium tuberculosis (Mtb), and SARS-CoV-2, with a focus on their molecular epidemiology in Botswana and their interactions with HIV.

SANTHE is an Africa Health Research Institute (AHRI) flagship programme funded by the Science for Africa Foundation through the DELTAS Africa programme; the Gates Foundation; Gilead Sciences Inc.; and the Ragon Institute of Mass General, MIT, and Harvard.