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Projects

SANTHE-related projects focus on acute infection studies, HIV-1 vaccine research, TB research, HIV/TB co-infections, associated morbidities, and emerging diseases in Africa like SARS-CoV-2. SANTHE scientists are also encouraged to conduct community and public engagement (CPE) as well as diversity, equity and inclusion (DEI) projects to complement their research work.

Fellowship (Tap to change)
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Fellowship 09 April 2024

Accessibility of point-of-care diagnostics for prevention of vertical disease transmission in rural primary health care clinics in Zambia

The main objective of Katoba’s study is to explore barriers and challenges related to the accessibility of point-of-care (POC) diagnostics for prevention of vertically transmitted infections in rural primary health care clinic (PHCs) settings of Zambia. The specific aims are:…

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Fellowship 11 April 2024

HIV-1 Genetic Diversity and Drug Resistance Mutations among Pregnant Women and Breastfeeding Mothers in Uganda

Uganda still falls short of the World Health Organisation’s targets of viral load suppression among the breastfeeding and pregnant women. This may be explained by increased levels of HIV-1 drug resistance mutations (HIV-DRMs) subsequently increasing the risk of vertical transmission…

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Fellowship 20 July 2026

Baseline immune reprogramming under chronic pathogen exposure: mechanisms and implications for immune function

Vaccines do not work equally well in everyone. One possible reason is that our immune systems are shaped by the infections we experience throughout our lives. People living in different parts of the world are exposed to different combinations of…

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Fellowship 20 July 2026

Characterisation of bnAb precursors and assessment of the B cell repertoires in health and in people living with HIV to inform Germline Targeting vaccine design

Germline-targeting (GT) vaccine strategies offer a promising approach to HIV vaccine design by engaging naïve B cell precursors and guiding their maturation into broadly neutralising antibodies (bnAbs) capable of countering HIV diversity. However, the success of GT vaccines depends on…

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SANTHE is an Africa Health Research Institute (AHRI) flagship programme funded by the Science for Africa Foundation through the DELTAS Africa programme; the Gates Foundation; Gilead Sciences Inc.; and the Ragon Institute of Mass General, MIT, and Harvard.

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