The UVRI-IAVI HIV Vaccine Programme was established in 2001 as a collaborative partnership between the Government of Uganda through the Ministry of Health represented by the Uganda Virus Research Institute (UVRI) and the International AIDS Vaccine Initiative (IAVI). It was developed to conduct a series of Phase I and II HIV vaccine trials and to run feasibility studies and other activities in preparation for future large scale HIV vaccine trials. All activities of the programme are aligned with Uganda's national strategic framework on HIV and AIDS and include: HIV vaccine research and development; community engagement and education; support to healthcare and voluntary counselling and testing structures; support for national and global advocacy; publications and media outreach; capacity building of the UVRI administrative core; operations. The programme’s Clinical Research Site is located at the UVRI campus in Entebbe, Uganda. Its aim is to further Uganda's contribution to the global search for an AIDS Vaccine and to support the country's efforts to accelerate HIV prevention, especially in vulnerable and high risk groups.