Dr Eunice Nduati PhD

Phone Number: 
+254 72 947 6677

Dr Eunice Nduati PhD

SANTHE Senior Researcher/Supervisor and Collaborative Grant Awardee

Eunice Nduati initially joined KWTRP in Nairobi working on antimalarial drug resistance. In 2005 she transferred to Kilifi to pursue her interest in the immunology of infectious diseases under the Biology and Pathology of the Malaria Parasite (BiolMalPar) PhD training programme. This was a collaborative programme with time spent between the UK and Kenya. Her thesis was on understanding host immune responses, specifically B-cell regulation in malaria. On returning to Kenya, she was awarded 6 months funding by BIOMALPAR/European Molecular Biology Laboratories (EMBL), a European Union Initiative to understand the role of soluble factors, such as the B cell activating factor (BAFF) on B-cell differentiation and function. She then successfully obtained a Wellcome Trust Training Fellowship, which has supported her current work on B-cell regulation in HIV infection and exposure. Her work aims at understanding whether exposure to HIV virus or antigens, antiretroviral drugs and/or an altered placental cytokine milieu, in utero, affects the developing immune system in infants born to HIV infected mothers but are themselves not infected. In HIV infection, she has been involved in understanding B cell phenotypic and functional changes in HIV infected children. More recently, through support from the Vaccine Immunology Science and Technology (VISTA) - International AIDS Vaccine Initiate programme, her work aims at understanding cellular mechanisms, largely T and B cell regulation on downstream antibody function.