Louis Kamulegeya

SANTHE Scientific Innovation Awardee

Makerere University, Kampala, Uganda


Assessing the role of micro-nutrient deficiency and immune system dysfunction among HIV-positive adults with pulmonary Tuberculosis at a public health facility in Uganda

Collaboration Interests
  • Non Mycobacterium TB diagnostics
  • Nutrition/Mal-nutrition and HIV
  • Tech Innovations in Tuberculosis diagnostics

Louis Kamulegeya is a Research Medical Doctor at the Makerere University Biomedical Research Centre with an interest in tuberculosis (TB) diagnostics research, especially among the HIV positives. His past experience includes research in nucleic acid amplification tests and rapid flow assays to which end results have contributed to national programming in TB diagnostics in Uganda. Kamulegeya’s research domain is implementation science with an interest in assessing how innovations and technology can be integrated within healthcare delivery, especially for TB diagnostics, patient care and monitoring, and population-level data, for studying trends and predictions. His current study is assessing how micro-nutrients may affect the severity of TB symptoms among HIV-positive patients and how their derangements may influence clinical outcomes and response to treatment. Micronutrient deficiencies among immune-suppressed TB patients remain under-studied, especially in TB endemic settings like Uganda where both TB and malnutrition are a double trouble. Understanding micro-nutrient changes among immune-suppressed TB patients will be critical in nutrition programme supplementation within this sub-population.

SANTHE is an Africa Health Research Institute (AHRI) flagship programme funded by the Science for Africa Foundation through the DELTAS Africa programme; the Bill & Melinda Gates Foundation; Gilead Sciences Inc.; and the Ragon Institute of Mass General, MIT, and Harvard.