Publications

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Flavonoid-based inhibition of cyclin-dependent kinase 9 without concomitant inhibition of histone deacetylases durably reinforces HIV latency

Authors Schonhofer, C., Yi, J., Sciorillo, A., Andrae-Marobela, K., Cochrane, A., Harris, M., Brumme, Z.L., Brockman, M.A., Mounzer, K., Hart, C., Gyampoh, K., Yuan, Z., Montaner, L.J., Tietjen, I.
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Acquired HIV-1 Protease Conformational Flexibility Associated with Lopinavir Failure May Shape the Outcome of Darunavir Therapy after Antiretroviral Therapy Switch

Authors Eche, S., Kumar, A., Sonela, N., Gordon, M.L.
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Increased Frequency of Inter-Subtype HIV-1 Recombinants Identified by Near Full-Length Virus Sequencing in Rwandan Acute Transmission Cohorts

Authors Umviligihozo, G., Muok, E., Nyirimihigo Gisa, E., Xu, R., Dilernia, D., Herard, K., Song, H., Qin, Q., Bizimana, J., Farmer, P., Hare, J., Gilmour, J., Allen, S., Karita, E., Hunter, E., Yue, L.
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A

A fast-screening dispersive liquid-liquid microextraction-gas chromatography-mass spectrometry method applied to the determination of efavirenz in human plasma samples

Authors Masenga, W., Paganotti, G.M., Seatla, K., Gaseitsiwe, S., Sichilongo, K.
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Persistent SARS-CoV-2 infection and intra-host evolution in association with advanced HIV infection (preprint)

Authors Karim, F., Moosa, M., Gosnell, B., Cele, S., Giandhari, J., Pillay, S., Tegally, H., Wilkinson, E., San, J., Msomi, N., Mlisana, K., Khan, K., Bernstein, M., Manickchund, N., Singh, L., Ramphal, U., COMMIT-KZN Team, Hanekom, W., Lessells, R., Sigal, A., de Oliveira, T.
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HIV-1 Gag-Pol Sequences from Ugandan Early Infections Reveal Sequence Variants Associated with Elevated Replication Capacity

Authors Kapaata, A., Balinda, S.N., Xu, R., Salazar, M.G., Herard, K., Brooks, K., Laban, K., Hare, J., Dilernia, D., Kamali, A., Ruzagira, E., Mukasa, F., Gilmour, J., Salazar-Gonzalez, J.F., Yue, L., Cotten, M., Hunter, E., Kaleebu, P.
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Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage

Authors Scheepers, C., Everatt, J., Amoako, D.G., Tegally, H., Wibmer, C.K., Mnguni, A., Ismail, A., Mahlangu, B., Lambson, B.E., Martin, D.P., Wilkinson, E., San, J.E., Giandhari, J., Manamela, N., Ntuli, N., Kgagudi, P., Cele, S., Richardson, S.I., Pillay, S., Mohale, T., Ramphal, U., Naidoo, Y., Khumalo, Z.T., Kwatra, G., Gray, G., Bekker, L.-G., Mad...
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Rapid replacement of the Beta variant by the Delta variant in South Africa (preprint)

Authors Tegally, H., Wilkinson, E., Althaus, C.L., Giovanetti, M., San, J.E., Giandhari, J., Pillay, S., Naidoo, Y., Ramphal, U., Msomi, N., Mlisana, K., Amoako, D.G., Everatt, J., Mohale, T., Nguni, A., Mahlangu, B., Ntuli, N., Khumalo, Z.T., Makatini, Z., Wolter, N., Scheepers, C., Ismail, A., Doolabh, D., Joseph, R., Strydom, A., Mendes, A., Davis, M...
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Comprehensive epitope mapping using polyclonally expanded human CD8 T cells and a two-step ELISpot assay for testing large peptide libraries

Authors Michelo, C.M., Dalel, J.A., Hayes, P., Fernandez, N., Fiore-Gartland, A., Kilembe, W., Tang, J., Streatfield, C., Gilmour, J., Hunter, E.
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Promoter Hypermethylation Analysis of Host Genes in Cervical Cancer Patients With and Without Human Immunodeficiency Virus in Botswana

Authors Tawe, L., Grover, S., Zetola, N., Robertson, E.S., Gaseitsiwe, S., Moyo, S., Kasvosve, I., Paganotti, G.M., Narasimhamurthy, M.
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SANTHE is an Africa Health Research Institute (AHRI) flagship programme funded by the Science for Africa Foundation through the DELTAS Africa programme; the Gates Foundation; Gilead Sciences Inc.; and the Ragon Institute of Mass General, MIT, and Harvard.