Publications

Nature

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity

Authors Meng, B., Abdullahi, A., Ferreira, I.A.T.M., Goonawardane, N., Saito, A., Kimura, I., Yamasoba, D., Gerber, P.P., Fatihi, S., Rathore, S., Zepeda, S.K., Papa, G., Kemp, S.A., Ikeda, T., Toyoda, M., Tan, T.S., Kuramochi, J., Mitsunaga, S., Ueno, T., Shirakawa, K., Takaori-Kondo, A., Brevini, T., Mallery, D.L., Charles, O.J., CITIID-NIHR BioResour...

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JCI Insight

Differential localization and limited cytotoxic potential of duodenal CD8+ T cells

Authors Mvaya, L., Khaba, T., Lakudzala, A.E., Nkosi, T., Jambo, N., Kadwala, I., Kankwatira, A., Patel, P.D., Gordon, M.A., Nyirenda, T.S., Jambo, K.C., Ndhlovu, Z.M.

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PLoS Pathog

An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults

Authors Vieira, V.A., Adland, E., Malone, D.F.G., Martin, M.P., Groll, A., Ansari, M.A., Garcia-Guerrero, M.C., Puertas, M.C., Muenchhoff, M., Guash, C.F., Brander, C., Martinez-Picado, J., Bamford, A., Tudor-Williams, G., Ndung’u, T., Walker, B.D., Ramsuran, V., Frater, J., Jooste, P., Peppa, D., Carrington, M., Goulder, P.J.R.

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Microbiology

SARS-CoV-2 Omicron spike mediated immune escape and tropism shift (preprint)

Authors Meng, B., Ferreira, I.A.T.M., Abdullahi, A., Goonawardane, N., Saito, A., Kimura, I., Yamasoba, D., Gerba, P.P., Fatihi, S., Rathore, S., Zepeda, S.K., Papa, G., Kemp, S.A., Ikeda, T., Toyoda, M., Tan, T.S., Kuramochi, J., Mitsunaga, S., Ueno, T., Shirakawa, K., Takaori-Kondo, A., Brevini, T., Mallery, D.L., Charles, O.J., CITIID-NIHR BioResourc...

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Biochem Pharmacol

Flavonoid-based inhibition of cyclin-dependent kinase 9 without concomitant inhibition of histone deacetylases durably reinforces HIV latency

Authors Schonhofer, C., Yi, J., Sciorillo, A., Andrae-Marobela, K., Cochrane, A., Harris, M., Brumme, Z.L., Brockman, M.A., Mounzer, K., Hart, C., Gyampoh, K., Yuan, Z., Montaner, L.J., Tietjen, I.

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Biomolecules

Acquired HIV-1 Protease Conformational Flexibility Associated with Lopinavir Failure May Shape the Outcome of Darunavir Therapy after Antiretroviral Therapy Switch

Authors Eche, S., Kumar, A., Sonela, N., Gordon, M.L.

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Front Microbiol

Increased Frequency of Inter-Subtype HIV-1 Recombinants Identified by Near Full-Length Virus Sequencing in Rwandan Acute Transmission Cohorts

Authors Umviligihozo, G., Muok, E., Nyirimihigo Gisa, E., Xu, R., Dilernia, D., Herard, K., Song, H., Qin, Q., Bizimana, J., Farmer, P., Hare, J., Gilmour, J., Allen, S., Karita, E., Hunter, E., Yue, L.

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Anal Bioanal Chem

A fast-screening dispersive liquid-liquid microextraction-gas chromatography-mass spectrometry method applied to the determination of efavirenz in human plasma samples

Authors Masenga, W., Paganotti, G.M., Seatla, K., Gaseitsiwe, S., Sichilongo, K.

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Infectious Diseases (except HIV/AIDS)

Persistent SARS-CoV-2 infection and intra-host evolution in association with advanced HIV infection (preprint)

Authors Karim, F., Moosa, M., Gosnell, B., Cele, S., Giandhari, J., Pillay, S., Tegally, H., Wilkinson, E., San, J., Msomi, N., Mlisana, K., Khan, K., Bernstein, M., Manickchund, N., Singh, L., Ramphal, U., COMMIT-KZN Team, Hanekom, W., Lessells, R., Sigal, A., de Oliveira, T.

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Viruses

HIV-1 Gag-Pol Sequences from Ugandan Early Infections Reveal Sequence Variants Associated with Elevated Replication Capacity

Authors Kapaata, A., Balinda, S.N., Xu, R., Salazar, M.G., Herard, K., Brooks, K., Laban, K., Hare, J., Dilernia, D., Kamali, A., Ruzagira, E., Mukasa, F., Gilmour, J., Salazar-Gonzalez, J.F., Yue, L., Cotten, M., Hunter, E., Kaleebu, P.

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